---------------- Tree given from ancestor ----------------
On the left:   Internal Node  Distance to parent =  233.67
On the left:   Internal Node  Distance to parent =   82.00
On the left:   Internal Node  Distance to parent =  101.00
On the left:   Leaf #1        Distance to parent =  173.00
On the right:  Leaf #2        Distance to parent =  175.00
On the right:  Leaf #5        Distance to parent =  340.00
On the right:  Leaf #4        Distance to parent =  232.33
On the right:  Leaf #3        Distance to parent =    0.00


                 ***  Heuristic Multiple Alignment  ***

*****************12345      ************************12543                  
IVGGYTCGANTVPYQVSL--NSGY--H-FCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGN----EQFIS
IVGGYECKAYSQAHQVSL--NSGY--H-FCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVTEGS----EQFIS
IVGGYKCEKNSQPWQVAV--INEY----LCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDEPF----AQRRL
IVGGWECEKHSQPWQVLV--ASRG--RAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT----GQVFQ
IVGGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSLIHPQWVLTAAHCVGPDVK-DLAALRVQLREQHLYYQDQLLP

                             **************************1234****************
ASKSIVHPSYN-----------SNTLNNDIMLIKLKSAASLNSRVASISLPTSCA--SAGTQCLISGWGNTKSSG
SSRVIRHPNYS-----------SYNIDNDIMLIKLSKPATLNTYVQPVALPTSCA--PAGTMCTVSGWGNTMSST
VRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTKEP--KVGSTCLASGWGSTNPSE
VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEP--ALGTTCYASGWGSIEPEE
VSRIIVHPQFY-----------TAEIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDE

34215  **************12345           *********12345**************34215 **12
TSYPD-VLKCLKAPILSDSSCKSAYP---------GQITSNMFCAGYLEGGKDSCQGDXGGPVVCSGK---LQ-G
-ADSD-KLQCLNIPILSYSDCNDSYP---------GMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGE---LQ-G
MVVSH-DLQCVNIHLLSNEKCIETYK---------DNVTDVMLCAGEMEGGKDTCAGDSGGPLICDGV---LQ-G
FLTPK-KLQCVDLHVISNDVCAQVHP---------QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGV---LQ-G
RLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAG

543     ***************************1
IVSWG-SGCAQKNKPGVYTKVCNYVSWIKQTIASN-
VVSWG-YGCAEPGNPGVYAKVCIFSDWLTSTMASY-
ITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP
ITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
VVSWG-EGCAQPNRPGIYTRVTYYLDWIHHYVPKKP


                  ***  Optimal Multiple Alignment  ***

IVGGYTCGANTVPYQVSL--NSGY--HFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGN----EQFISA
IVGGYECKAYSQAHQVSL--NSGY--HFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVTEGS----EQFISS
IVGGYKCEKNSQPWQVAV--INEY---LCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDEPF----AQRRLV
IVGGWECEKHSQPWQVLV--ASRG-RAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT----GQVFQV
IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD-LAALRVQLREQHLYYQDQLLPV

SKSIVHPSYN-----------SNTLNNDIMLIKLKSAASLNSRVASISLPTSCA--SAGTQCLISGWGNTKSSGT
SRVIRHPNYS-----------SYNIDNDIMLIKLSKPATLNTYVQPVALPTSCA--PAGTMCTVSGWGNTMSS-T
RQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTKEP--KVGSTCLASGWGSTNPSEM
SHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEP--ALGTTCYASGWGSIEPEEF
SRIIVHPQFY-----------TAEIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDER

SYPD-VLKCLKAPILSDSSCKSAYP---------GQITSNMFCAGYLEGGKDSCQGDXGGPVVCSGK---LQ-GI
ADSD-KLQCLNIPILSYSDCNDSYP---------GMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGE---LQ-GV
VVSH-DLQCVNIHLLSNEKCIETYK---------DNVTDVMLCAGEMEGGKDTCAGDSGGPLICDGV---LQ-GI
LTPK-KLQCVDLHVISNDVCAQVHP---------QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGV---LQ-GI
LPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGV

VSWGSG-CAQKNKPGVYTKVCNYVSWIKQTIASN-
VSWGYG-CAEPGNPGVYAKVCIFSDWLTSTMASY-
TSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP
TSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
VSWGEG-CAQPNRPGIYTRVTYYLDWIHHYVPKKP

End gaps not penalized.
Costfile:                   pam250
Alignment cost:   68277     Lower bound:   67982
Delta:              295     Max. Delta:      303

Sequences  Proj. Cost  Pair. Cost  Epsilon  Max. Epsi.  Weight  Weight*Cost
  1   2        2952        2951        1         5         4       11808
  1   3        3382        3380        2         5         1        3382
  1   4        3430        3418       12        12         1        3430
  1   5        3552        3544        8         7         2        7104
  2   3        3403        3399        4         5         1        3403
  2   4        3456        3441       15        11         1        3456
  2   5        3607        3597       10         8         2        7214
  3   4        3306        3304        2         5         4       13224
  3   5        3828        3773       55        50         2        7656
  4   5        3800        3748       52        50         2        7600
Elapsed time =   0.767
